Studies of HPD: Chemical Composition and in Vitro Photosensitization
Photoactivated porphyrins are at present being evaluated for use in cancer therapy (Kelly and Snell, 1976; Dougherty et al., 1978). The method is based on two properties of particular porphyrins: Their tumor-localizing ability (Gomer and Dougherty, 1979) and their photodynamic effect (for a review see Moan and Christensen, 1980). Porphyrin photosensitization is also manifested in the skin of patients suffering from porphyrias.
KeywordsSister Chromatid Exchange Hydrophobic Component Photodynamic Effect Hydrophilic Fraction Cell Inactivation
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