Studies of HPD: Chemical Composition and in Vitro Photosensitization

  • Terje Christensen
  • Johan Moan
  • James Brown McGhie
  • Helga Waksvik
  • Hein Stigum
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 160)


Photoactivated porphyrins are at present being evaluated for use in cancer therapy (Kelly and Snell, 1976; Dougherty et al., 1978). The method is based on two properties of particular porphyrins: Their tumor-localizing ability (Gomer and Dougherty, 1979) and their photodynamic effect (for a review see Moan and Christensen, 1980). Porphyrin photosensitization is also manifested in the skin of patients suffering from porphyrias.


Sister Chromatid Exchange Hydrophobic Component Photodynamic Effect Hydrophilic Fraction Cell Inactivation 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Terje Christensen
    • 1
  • Johan Moan
    • 1
  • James Brown McGhie
    • 1
  • Helga Waksvik
    • 1
  • Hein Stigum
    • 1
  1. 1.Norsk Hydro’s Institute for Cancer ResearchMontebello, Oslo 3Norway

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