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Porphyrin Localizing Phenomena

  • David Kessel
  • Ta-Hsu Chou
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 160)

Abstract

The use of the porphyrin product HPD1 for tumor localization (1,2) and therapy (2–5) has been described. One report on an analysis of HPD appeared in 1980 (6) and other such reports are contained in this book. In order to characterize the events leading to tumor localization by HPD, it will be necessary to delineate active components in the product, the nature of any porphyrin transformations associated with the localization process and loci of binding of localized fluorescent porphyrins within the tumor cell.

Keywords

L1210 Cell Complete Growth Medium Fresh Growth Medium Leukemia L1210 Cell Hydrophobic Contaminant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

HPD

hematoporphyrin derivative [product of alkaline hydrolysis after acetylation]

HP

hematoporphyrin

HVD

monohydroxyethyl-monovinyldeuteroporphyrin

PP

protoporphyrin

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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • David Kessel
    • 1
  • Ta-Hsu Chou
    • 1
  1. 1.Departments of Pharmacology and OncologyWayne State University School of MedicineDetroitUSA

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