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ICU Monitoring of Ventilation Distribution

  • Richard R. Mitchell
  • Ross M. Wilson
  • Dianne Sierra

Abstract

Routine monitoring of lung volume in mechanically ventilated patients may be useful for detecting the onset of atelectasis, pulmonary edema, pneumothorax, and mucous plug airway obstruction. The oxygen eashin method was developed to monitor FRC in the intensive care unit(ICU)1. Fast and slow space components were observed in normalized semilogarithmic plots of mixed expired O2 fraction following changes in the ventilator inspired O2 fraction for ventilators with small internal mixing volumes2. This suggested the possibility of obtaining estimates of ventilation and volume in a two compartment model of the lung and a detailed digital computer simulation showed no significant difference between estimates of two compartment parameters using O2 washin or N2 washout data3.

Keywords

Dead Space Ventilation Mode Peep Level Oxygen Fraction Leftward Shift 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    R.R. Mitchell, R.M. Wilson, L. Holzapfel, A.M. Benis, D. Sierra, and J.J. Osborn, The oxygen washin method for monitoring functional residual capacity, submitted to Critical Care Medicine.Google Scholar
  2. 2.
    D.H. McClung, and R.R. Mitchell, Monitoring of functional residual capacity in an intensive care unit, San Diego Biomed. Symp. Proc., 15: 403, 1976.Google Scholar
  3. 3.
    R.R. Mitchell, D.H. McClung, and A.M. Bagniewski, Measurement of ventilation distribution with a patient monitoring system, San Diego Biomed. Symp. Proc., 17: 277, 1978.Google Scholar
  4. 4.
    S.M. Lewis, J.W. Evans, and A.A. Jalowayski, Continuous distributions of specific ventilation recovered from inert gas washout. J. App. Physiol.: Respirat. Environ. Exercise Physiol. 44: 416–423, 1978.Google Scholar
  5. 5.
    P.D. Wagner, Information content of the multibreath nitrogen washout, J. Appl. Physiol.: Respirat., Environ. Exercise physiol. 46: 579–587, 1979.Google Scholar
  6. 6.
    J.J. Osborn, J.O. Beaumont, J.C.A. Raison, and R.P. Abbott, Computation for quantitative on line measurements in an intensive care ward. In “Comp. Biomed. Res.: (Stacey and Waxman, Eds.), Vol. III, pp. 207–236. Academic Press, New York, 1969.Google Scholar
  7. 7.
    J.J. Osborn, A Flowmeter for respiratory monitoring, Crit. Care Med. 6: 349, 1978.MathSciNetCrossRefGoogle Scholar
  8. 8.
    C.L. Lawson and R.J. Hanson, Solving Least Squares Problems, Prentice Hall, New Jersey, 1974, p. 304.MATHGoogle Scholar
  9. 9.
    J.W. Evans and P.D. Wagner, Limits on Va/Q distribution from analysis of experimental inert gas elimination, J. Appl. Physiol., 42: 889–898, 1977.Google Scholar
  10. 10.
    S. Lewis and C.J. Martin, Characteristics of the washout dead space, Res. Physiol. 36: 51–63, 1979.CrossRefGoogle Scholar
  11. 11.
    R. Dueck, P.D. Wagner, and J.B. West, Effects of positive and expiratory pressure on gas exchange in dogs with normal and edematous lungs, Anesthesiology 47: 359–366, 1977.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Richard R. Mitchell
    • 1
  • Ross M. Wilson
    • 1
  • Dianne Sierra
    • 1
  1. 1.The Institute of Biomedical Engineering SciencesThe Institutes of Medical SciencesSan FranciscoUSA

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