A Standard Artificial Lung for System Calibration in Physiological Gas Exchange Measurement
The measurement of metabolic gas exchange in bags or balloons is direct and obvious; mixed expired gas is collected as the entire alveolar ventilation combined with the dead space ventilation. Recent approaches to automation of gas exchange measurement1,2,5,7,8,9 have in common the elimination of bags for collection of the entire expired sample; the approaches vary, but each method is susceptible to error in determination of the mixed expired gases or measurement of the entire volume or both. The typical calibration procedure is to calibrate the individual analyzers and transducers in the system separately using large calibration syringes, precision gases, etc. It is assumed that if the individual components have been calibrated, the system is calibrated. This paper describes a Standard Artificial Lung (SAL) for system calibration of metabolic measurements devices, and it presents the results of testing some of these systems.
KeywordsSystem Calibration Inspire Volume Dead Space Ventilation Expire Minute Volume Metabolic Measurement Cart
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- 1.W.L. Beaver, K. Wasserman, B.J. Whipp, On-line computer analysis and breath-by-breath graphical display of exercise function tests, J. Appl. Physiol. 23: 128–132, 1973.Google Scholar
- 4.G. Lister, Jr., J.I.E. Hoffman, A.M. Rudolph, Measurement of oxygen consumption: assessing the accuracy of a method, J. Appl. Physiol. Environ. Exercise Physiol., 43: 916–917, 1977.Google Scholar
- 5.A.C. Norton, V. Mashikian, J.H. Wilmore, C.D. Rader, Development and evaluation of a metabolic measurement cart, Proc. S. Diego Biomed. Symp., 15: 139–145, 1976.Google Scholar
- 6.A.C. Norton, J.J. Wilmore, Effects of water vapor on respiratory gas measurements and calculations, The NSCPT Analyzer, 9: 6–9, 1979.Google Scholar
- 7.J.H. Wilmore, D.L. Costill, Semiautomated systems approach to the assessment of oxygen uptake during exercise, J. Appl. Physiol., 36: 618–620, 1974.Google Scholar
- 8.J.H. Wilmore, J.A. Davis, A.C. Norton, An automated system for assessing metaboliç and respiratory function during exercise, J. Appl. Physiol., 40: 619–624, 1976.Google Scholar
- 9.H.U. Wessel, R.L. Stout, C.K. Bastamier, M.H. Paul, Computer gesteuerte Belastungs–unter suchungen in der Kinder Kardiologie: Atemzug-zu-atemzug Analyse von Ventilation and alveolaerem Gas austausch, Biomed Technik, 22: 345–346, 1977.Google Scholar