Carcinogenic Risk Assessment—The Consequences of Believing Models
Part of the
Basic Life Sciences
To estimate risks to humans from carcinogens requires extrapolation from animal or other data. Any such extrapolation must be made in the context of a model or models, but no current consensus exists as to which models are correct. There is no shortage of suggested models for this task, each motivated by theoretical arguments, but the differences among them can lead to enormously different predictions. Furthermore, they often lack any practical demonstration of validity.
KeywordsDose Measure Random Error Term Unit Slope B6C3F1 Mouse Carcinogenic Potency
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Plenum Press, New York 1983