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Role of Natural Killer Cells and of Interferon in Natural Resistance against Virus Infections

  • H. Kirchner
  • H. Engler
  • R. Zawatzky
  • L. Schindler
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 155)

Abstract

There are a number of experimental findings that are fairly well established:
  1. (a)

    Interferons cause an antiviral effect in tissue culture (1).

     
  2. (b)

    Injection of interferon causes antiviral protection in vivo (for a review see Ref. 2).

     
  3. (c)

    Injection of a variety of viruses causes rapid interferon production in vivo, both at the infection site (for example in the peritoneal cavity) and in the serum (3).

     
  4. (d)

    Injection of interferon or interferon inducers (including viruses) causes activation of Natural Killer (NK) cells in vivo (4).

     

Keywords

Herpes Simplex Virus Infection Natural Killer Activity Normal Rabbit Serum Peritoneal Exudate Peritoneal Exudate Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • H. Kirchner
    • 1
  • H. Engler
    • 1
  • R. Zawatzky
    • 1
  • L. Schindler
    • 1
  1. 1.Institute of Virus ResearchGerman Cancer Research CenterHeidelbergGermany

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