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Tumoricidal and Immunoregulatory Activity of Macrophages from Human Ovarian Carcinomas

  • Giuseppe Peri
  • Andrea Biondi
  • Barbara Bottazzi
  • Nadia Polentarutti
  • Claudio Bordignon
  • Alberto Mantovani
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 155)

Abstract

Macrophages are a major component of the lymphoreticular infiltrate of experimental and human tumors but their in vivo significance remains to be elucidated (1). Macrophages have diverse functions, including the capacity to interact directly with tumor cells and with lymphoid cells. The results summarized here were aimed at elucidating the tumoricidal and immunomodulatory capacity of diverse human macrophage populations including tumor-associated macrophages.

Keywords

Ovarian Carcinoma Blood Monocyte Natural Killer Activity Tumor Associate Macrophage Tumoricidal Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Giuseppe Peri
    • 1
  • Andrea Biondi
    • 1
  • Barbara Bottazzi
    • 1
  • Nadia Polentarutti
    • 1
  • Claudio Bordignon
    • 1
  • Alberto Mantovani
    • 1
  1. 1.Istituto di Ricerche Farmacologiche “Mario Negri”MilanItaly

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