Stimulation by Various Lectins of Intracellular Killing of Micro-Organisms by Phagocytic Cells
The ingestion of bacteria by phagocytes is accompanied by a metabolic burst during which oxygen is consumed and converted into Superoxide anion and hydrogen peroxide. Studies performed in the last decade have shown a correlation between the generation of these oxygen intermediates and the microbicidal and tumoricidal activity of the cells (1–3). Recently, we described the extracellular requirement for serum factors, especially IgG and C3b, by monocytes and granulocytes to obtain maximal intracellular killing of micro-organisms (4–6).
KeywordsPhate Buffer Saline Rosette Formation Tumoricidal Activity Intracellular Killing Soybean Lectin
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- 5.Leijh, P. C. J., Zwet, Th. L. van, and Furth, R. van, Inf. Immun. 30:421, 1980.Google Scholar
- 6.Leijh, P. C. J., Barselaar, M. Th. van den, Daha, M. R., and Furth, R. van, Inf. Immun. 33:714, 1981.Google Scholar
- 7.Furth, R. van, Zwet, Th. L. van, and Leijh, P. C.J., in “Handbook of Experimental Immunology” (D. M. Weir, ed.), Ch. 32, Black-well Scientific Publications, Oxford, 1978.Google Scholar