Stimulation by Various Lectins of Intracellular Killing of Micro-Organisms by Phagocytic Cells

  • P. C. J. Leijh
  • Th. L. van Zwet
  • R. van Furth
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 155)


The ingestion of bacteria by phagocytes is accompanied by a metabolic burst during which oxygen is consumed and converted into Superoxide anion and hydrogen peroxide. Studies performed in the last decade have shown a correlation between the generation of these oxygen intermediates and the microbicidal and tumoricidal activity of the cells (1–3). Recently, we described the extracellular requirement for serum factors, especially IgG and C3b, by monocytes and granulocytes to obtain maximal intracellular killing of micro-organisms (4–6).


Phate Buffer Saline Rosette Formation Tumoricidal Activity Intracellular Killing Soybean Lectin 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • P. C. J. Leijh
    • 1
  • Th. L. van Zwet
    • 1
  • R. van Furth
    • 1
  1. 1.Department of Infectious DiseasesUniversity HospitalLeidenThe Netherlands

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