Splenic Function in Primary Glomerulonephritis

  • Susan Lawrence
  • B. A. Pussell
  • J. A. Charlesworth
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 155)


Recent studies have shown that the tissue distribution and deposition of immune complexes may be altered by activation or saturation of the reticuloendothelial system (RES) (1–3). RES hypofunction has been demonstrated in patients with systemic lupus erythematosus (4), systemic vasculitis (5) and mixed cryoglobulinemia with nephritis (6). These authors suggested that defective RES function may have contributed to the pathogenesis of the nephritis found in these putative immune complex-mediated diseases.


Glomerular Basement Membrane Clearance Time Mixed Cryoglobulinemia Membranous Glomerulonephritis Splenic Function 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Susan Lawrence
    • 1
    • 2
  • B. A. Pussell
    • 1
    • 2
  • J. A. Charlesworth
    • 1
    • 2
  1. 1.Department of NephrologyPrince Henry HospitalSydneyAustralia
  2. 2.The Renal UnitWollongong HospitalWollongongAustralia

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