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Peritoneal Macrophages Release Prostaglandin E and Thromboxane B2 in Response to C3b

  • Ulrich Hadding
  • Hans-Peter Hartung
  • Heinrich Rasokat
  • Diethard Gemsa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 155)

Abstract

Macrophages have surface receptors for C3b, the larger product cleaved from complement component C3 upon activation of both the classical and alternative complement pathways (1). We have investigated whether or not C3b stimulates macrophages to release prostaglandin E (PGE) and thromboxane B2 (TXB2), metabolites of arachidonic acid produced in the cyclooxygenase pathway (2).

Keywords

Arachidonic Acid Peritoneal Macrophage Oxidative Burst Alternative Complement Pathway Cobra Venom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Ulrich Hadding
    • 1
    • 2
  • Hans-Peter Hartung
    • 1
    • 2
  • Heinrich Rasokat
    • 1
    • 2
  • Diethard Gemsa
    • 1
    • 2
  1. 1.Inst. for Medical MicrobiologyUniv. MainzMainzGermany
  2. 2.Inst. of ImmunologyUniv. HeidelbergGermany

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