Influence of Macrophage Activation on the Synthesis of Complement Components C2, C3, C4
Macrophages are a major site of complement synthesis. In the guinea pig production of complement components C1, C2, C4, C3, D, B, and P by peritoneal macrophages has been demonstrated (reviewed in Ref. 1). Whereas marked differences exist in biological activity between resident, elicited and activated macrophages (2), we investigated whether this holds true for the synthesis and secretion of complement components C2, C3, and C4.
KeywordsHuman Serum Albumin Peritoneal Macrophage Hemolytic Activity Complement Component Hemolytic Assay
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