Influence of Macrophage Activation on the Synthesis of Complement Components C2, C3, C4

  • Hans-Peter Hartung
  • Bernd Zanker
  • Dieter Bitter-Suermann
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 155)


Macrophages are a major site of complement synthesis. In the guinea pig production of complement components C1, C2, C4, C3, D, B, and P by peritoneal macrophages has been demonstrated (reviewed in Ref. 1). Whereas marked differences exist in biological activity between resident, elicited and activated macrophages (2), we investigated whether this holds true for the synthesis and secretion of complement components C2, C3, and C4.


Human Serum Albumin Peritoneal Macrophage Hemolytic Activity Complement Component Hemolytic Assay 


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Hans-Peter Hartung
    • 1
  • Bernd Zanker
    • 1
  • Dieter Bitter-Suermann
    • 1
  1. 1.Institute of Medical MicrobiologyUniversity of MainzMainzGermany

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