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Serum Blocking Factors in Tumor Bearing Hosts: The Value of Extended Plasma Exchange on In Vitro Immune Parameters of Patients with Advanced Cancer

  • Peter Schuff-Werner
  • Jörg-Herbert Beyer
  • Gerd Arno Nagel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 155)

Abstract

Experimental and clinical studies (reviewed in Ref. 1) indicate that serum blocking factors may alter immunological and inflammatory responses promoting tumor growth. In recent years, many plasma components including as yet undefined soluble factors especially glyco-proteins have been described as inhibitory in in vitro and in vivo bio-assays. It is still controversial if these factors are tumor products or if they are consequent to a tumor induced host response. In the present study, we investigated the possibility of reducing or eliminating such factors by large volume plasma-exchange with the aim of modulating the host tumor response.

Keywords

Plasma Exchange Blocking Activity Tumor Bearing Serum Blocking Tritiated Thymidine Uptake 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Schuff-Werner, P., Brattig, N., Beyer, J.-H., Bartel, J., Köstering, H., Berg, P. A., Nagel, G. A., Plasmapheresesym-posium Göttingen, 5.–6.12.1980, S. Karger Verlag, Basel, 1982.Google Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Peter Schuff-Werner
    • 1
  • Jörg-Herbert Beyer
    • 1
  • Gerd Arno Nagel
    • 1
  1. 1.Division of Oncology, Department of MedicineUniversity ClinicsGoettingenGermany

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