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Analysis of Hydroxy Acids

  • Walter C. Hubbard
  • Douglass F. Taber
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 54)

Abstract

The variety of hydroxy acids derived from arachidonic acid and other polyunsaturated fatty acids that have been isolated from mammalian tissues is increasing rapidly. These hydroxy acids are products of metabolism initiated by several different enzymes. These include fatty acid cyclooxygenase [1–3], 5-lipoxygenase [4–24], 12lipoxygenase [25–31], 15-lipoxygenase [32–36], and thyroid iodide peroxidase [37–39]. In addition, hydroxy acids derived from arachidonic acid and other polyunsaturated fatty acids have been isolated from mammalian tissues which may be products of enzymes that have not been classified [40–45]. In some instances, hydroxy acids isolated from mammalian tissues may be nonenzymatically formed oxygenation products of arachidonic acid and other polyunsaturated fatty acids.

Keywords

Arachidonic Acid Polyunsaturated Fatty Acid Mammalian Tissue Hydroxy Acid Hydroxyl Moiety 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Walter C. Hubbard
    • 1
  • Douglass F. Taber
    • 1
  1. 1.Department of PharmacologyVanderbilt UniversityNashvilleUSA

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