An in Vivo Aggregometer

  • C. P. Page
  • W. Paul
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 54)


The method of aggregometry introduced by Born [1] in 1962 has been used extensively to study platelet aggregation and disaggregation in vitro and ex vivo. Although it is generally accepted that in vitro data does not always reflect in vivo data [2], fewer studies have been undertaken on platelets in vivo. Such, in vivo studies are limited by the cumbersome and invasive nature of existing techniques [3] which has prompted development of a simple, minimally invasive technique for the continuous monitoring of radiolabeled platelets in vivo [4].


Platelet Aggregation Adenosine Diphosphate Prostaglandin Endoperoxide Coeliac Artery Study Platelet Aggregation 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • C. P. Page
    • 1
  • W. Paul
    • 1
  1. 1.Department of Clinical PharmacologyCardiothoracic InstituteLondonEngland

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