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Inhibition of Arachidonic Acid Metabolism

  • J. A. Salmon
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 54)

Abstract

Prostaglandins and related compounds derived from arachidonic acid have been implicated as the causative factor(s) in the pathogenesis of many conditions including inflammation, asthma, Bartter’s syndrome, dysmenorrhoea, threatened abortion and premature labour. Thus, compounds which inhibit metabolism of arachidonic acid have a wide therapeutic potential. Additionally, such inhibitors should prove invaluable to the experimental investigator to enable, for example, evaluation of the physiological roles of the prostaglandins.

Keywords

Arachidonic Acid Arachidonic Acid Metabolism Prostaglandin Biosynthesis Prostaglandin Synthetase Prostaglandin Endoperoxide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • J. A. Salmon
    • 1
  1. 1.Department of ProstaglandinResearch Wellcome Research LaboratoriesBeckenham, KentUK

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