Hyperthermia pp 123-144 | Cite as

Oxygen Effects in Radiobiology

  • C. J. Koch
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 157)


In the field of Radiobiology, (a good recent text is “Radiobiology for the Radiobiologist”; Hall, 1978) the ‘Oxygen Effect’ is understood to mean the increased sensitivity of cells to damage fron ionizing radiation as the concentration of oxygen increases from 0 to about 20,000 ppm*. Above 20,000–50,000 ppm the radiation sensitivity remains about the same (see Ling et al, 1981 for one of the most accurate assessments). But oxygen affects many aspects of cell biology and (bio) chemistry and several of these are important in radiobiology. The purpose of this short review is to describe several effects of oxygen pertinent to radiobiology and to indicate problem areas where the interaction of the Radiation Research Society and International Society for Oxygen Transport to Tissue might be most beneficial. The reference list is by no means comprehensive, but representative articles are listed where appropriate.


Oxygen Tension Hyperbaric Oxygen Hypoxic Cell Oxygen Effect Aerobic Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • C. J. Koch
    • 1
  1. 1.Radiobiology, Cross Cancer InstituteEdmontonCanada

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