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Adjuvant Action of Bacterial Endotoxins on Antibody Formation

A Historical Perspective
  • Arthur G. Johnson

Abstract

One of the most dramatic of the potentially beneficial actions of the endotoxins derived from gram-negative bacteria has been their capacity to elevate antibody levels to unrelated antigens in animals. This truly profound effect of the isolated lipopolysaccharide component (LPS) has been known for over 25 years (Johnson et al., 1956), and has found application in many experimental immunology laboratories throughout the world.

Keywords

Typhoid Fever Serratia Marcescens Antibody Formation Pertussis Vaccine Bacterial Endotoxin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Arthur G. Johnson
    • 1
  1. 1.Department of Medical Microbiology/ImmunologyUniversity of MinnesotaDuluthMinnesotaUSA

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