5-Hydroxytryptamine Receptors in Brain

  • G. Fillion
Part of the Handbook of Psychopharmacology book series (HBKPS)


The biogenic amine, 5-hydroxytryptamine (5-HT), was first described in extracts of natural materials almost 30 years ago (see review by Collier, 1957). Twarog and Page (1953) and Amin et al. (1954) were the first to demonstrate, on pharmacological evidence, the occurence of 5-HT in the central nervous system of the dog which was confirmed by Bogdanski et al. (1956) and Correale (1956) by physicochemical criteria.


Adenylate Cyclase Serotonin Receptor Adenylate Cyclase Activity Synaptic Membrane Synaptic Plasma Membrane 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • G. Fillion
    • 1
  1. 1.Pharmacology DepartmentPasteur InstituteParisFrance

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