Mutation InVivo in Human Somatic Cells: Studies Using Peripheral Blood Mononuclear Cells

  • Richard J. Albertini
  • David L. Sylwester
  • Bruce D. Dannenberg
  • Elizabeth F. Allen
Part of the Basic Life Sciences book series (volume 6)


We review here our efforts to develop a direct mutagenicity test system for detecting somatic cell mutations occurring in vivo in man. Our specific goal is to provide a useful test for directly quantifying mutant cells in human blood samples.


Purine Analog Diploid Human Fibroblast Direct Mutagenicity Label Nucleus Human Somatic Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Richard J. Albertini
    • 1
    • 2
  • David L. Sylwester
    • 1
  • Bruce D. Dannenberg
    • 1
  • Elizabeth F. Allen
    • 1
  1. 1.Department of Medicine and Medical MicrobiologyUniversity of VermontBurlingtonUSA
  2. 2.Department of MedicineUniversity of Vermont College of MedicineBurlingtonUSA

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