Spontaneous Regression of Metastatic Renal Cell Carcinoma and Its Significance in Assessing Response of Such Patients to Chemotherapy

  • R. T. D. Oliver
  • R. Stuart-Harris
  • P. F. M. Wrigley
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 53)


Spontaneous complete regression of tumour metastases received recognition as a genuine phenomenon following the carefully documented study of literature reports by Everson and Cole (1). Renal cell carcinoma was the tumour most frequently reported to undergo spontaneous complete regression, although in that series for only four of 26 patients was there histological documentation that the lung shadows contained malignant cells. In the recent review by Fairlamb (2) at least 15/67 lived five years although half subsequently died of recurrence of their disease up to 15 years later.


Renal Cell Carcinoma Metastatic Renal Cell Carcinoma Renal Carcinoma Spontaneous Regression Vinca Alkaloid 
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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • R. T. D. Oliver
    • 1
  • R. Stuart-Harris
    • 1
  • P. F. M. Wrigley
    • 1
  1. 1.Institue of Urology and St- Bartholomew’s HospitalLondonEngland

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