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Histochemical Detection of Steroid Binding Sites in Human Renal Tissue and Renal Cell Carcinoma: A Preliminary Report of Work in Progress

  • R. J. Macchia
  • L. P. Pertschuk
  • G. J. Wise
  • P. Shapiro
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 53)

Abstract

The degree of interest in the hormonal milieu as a factor influencing the natural history of renal cell carcinoma is, perhaps, out of proportion to what is warranted by the cumulative experience. Controversy regarding this topic might best be relegated to the medical equivalent of Shakespeare’s “Much Ado About Nothing”. As a minor offshoot of our binding site studies involving prostatic cancer (described in another section of this book: see ‘Histochemical determination of androgen binding in prostatic adenocarcinoma: clinical correlation’) we succumbed to this apparently irresistable phenomenon. The following is a preliminary report on work in progress.

Keywords

Renal Cell Carcinoma Metastatic Renal Cell Carcinoma Prostatic Adenocarcinoma Distal Convoluted Tubule Hormonal Milieu 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    L.P. Pertschuk, E.E. Carvounis, E.H. Tobin, and E. Gaetjens, Renal glomerular steroid hormone binding. Detection by fluorescent microscopy. J. Steroid Biochem. 13: 1115 (1980).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • R. J. Macchia
    • 1
  • L. P. Pertschuk
    • 1
  • G. J. Wise
    • 2
  • P. Shapiro
    • 1
  1. 1.Downstate Medical CenterThe State University of New YorkBrooklynUSA
  2. 2.The Maimonides Medical CenterBrooklynUSA

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