The Evaluation of Chemotherapy in a Murine Renal Adenocarcinoma
A spontaneously arising renal adenocarcinoma in a male Wistar-Lewis rat has been used over the past three years as a testing system for various chemotherapeutic agents, used alone or in combination. We have also utilized this model in an effort to evaluate the ability of cytoreductive surgery to render chemotherapy more effective. Finally, we have looked at the sensitivity of this tumor to hyperthermia delivered alone or in combination with cyclophosphamide.
KeywordsCytoreductive Surgery Tumor Weight Nodule Model Metastatic Model Intraperitoneal Tumor
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