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Pulmonary and Osseous Metastases in Prostatic Cancer: Methods of Quantitative Assessment

  • D. P. Byar
  • J. A. Hovsepian
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 53)

Abstract

The extent of bone and lung metastases in each of eight sites was rated on a semi-quantitative scale using pretreatment films for 102 patients with known metastases at diagnosis. A statistical analysis revealed significant correlation between shortened patient survival and a combination of the number of sites involved and the extent of involvement in those sites. Correlations were also identified with acid phosphatase, pain and performance ratings, but not with tumor grade. Examination of several films for patients treated with endocrine therapy showed that some patients who ultimately show improvement may initially show pseudo-progression.

Keywords

Bone Metastasis Acid Phosphatase Lung Metastasis True Progression Serial Film 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    J. Hovsepian and D. Byar, Carcinoma of prostate. Correlation between radiologic quantitation of metastases and patient survival, Urology 6:11–16 (1975).PubMedCrossRefGoogle Scholar
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    J. Hovsepian and D. Byar, Quantitative radiology for staging and prognosis of patients with advanced prostatic carcinoma: Correlations with other pretreatment characteristics, Urology 14:145–150 (1979).PubMedCrossRefGoogle Scholar
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    J. Hovsepian, D. Byar and the VACURG, Pseudo-progression and regression of bone metastases during endocrine therapy of prostatic adenocarcinoma, Proc. Amer. Soc. Clinical Oncology 21:421 (Abstract) (1980).Google Scholar

Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • D. P. Byar
    • 1
  • J. A. Hovsepian
    • 2
  1. 1.National Cancer InstituteBethesdaUSA
  2. 2.Stanford University School of MedicineCaliforniaUSA

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