The Clinical Value of the Serum Acid Phosphatase in Carcinoma of the Prostate

  • B. Richards
  • R. Sylvester
  • M. de Pauw
  • the EORTC Urological Group
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 53)


A phosphatase which was particularly active at an acid pH was shown to be present in red blood cells in 1924 (1). Acid phosphatases are also present in leucocytes, platelets, osteoclasts, reticuloendothelial cells, and in liver, kidney, spleen and other organs. Their clinical importance derives from the fact that the concentration of the enzyme is far greater in the prostate than in any other human tissue (2).


Prostatic Cancer Acid Phosphatase Prostatic Acid Phosphatase Bony Metastasis Estramustine Phosphate 
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Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • B. Richards
    • 1
  • R. Sylvester
    • 2
  • M. de Pauw
    • 2
  • the EORTC Urological Group
  1. 1.York District HospitalYorkUK
  2. 2.EORTC Data CentreBrusselsBelgium

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