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Immunological Assays for Prostatic Acid Phosphatase

  • N. A. Romas
  • M. Tannenbaum
Part of the NATO Advanced Science Institutes Series book series (NSSA, volume 53)

Abstract

Several immunological assays for the determination of prostatic acid phosphatase (PAP) in the diagnosis of prostate carcinoma have been developed since the demonstration of a specific antibody to PAP. Some of these assays have demonstrated increased specificity and a moderate degree of increased sensitivity over standard biochemical assays. The data presented should be used as routine screening tests for the early detection of prostatic carcinoma.

Keywords

Prostatic Carcinoma Moderate Degree Prostatic Hypertrophy Benign Prostatic Hypertrophy Prostatic Acid Phosphatase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    A. Gutman and E Gutman, An “acid” phosphatase occuring in the serum of patients with metastasizing carcinoma of the prostate gland, J. Clin. Invest. 17:473 (1938).PubMedCrossRefGoogle Scholar
  2. 2.
    N. Romas, K. Hsu, P. Ng, M. Pitts, P. Tomashefsky, and M. Tannenbaum, Counterimmunoelectrophoretic studies of serum prostatic acid phosphatase, Prostate 1:451 (1980).PubMedCrossRefGoogle Scholar
  3. 3.
    G. Andras, A.G. Foti, J. Fenimore Cooper, H. Herschman, and R.R. Malvaez, Detection of Prostatic Cancer by Solid Phase Radioimmunoassay of Serum Prostatic Acid Phosphatase, New Eng. J. Med. 297:1357 (1977).CrossRefGoogle Scholar
  4. 4.
    A. Bruce, D. Mahan, L. Sullivan, and L. Goldenberg, The significance of prostatic acid phosphatase in adenocarcinoma of the prostate, J. Urol. 125:357 (1981).PubMedGoogle Scholar
  5. 5.
    G. Murphy, T. Chu, and J. Karr, Prostatic acid phosphatase — the developing experience, Clin. Biochem. 12:226 (1979).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1983

Authors and Affiliations

  • N. A. Romas
    • 1
  • M. Tannenbaum
    • 1
  1. 1.Columbia-Presbyterian Medical CenterNew YorkUSA

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