Immunological Detection of Prostatic Acid Phosphatase: Five Years’ Experience
In 1976, a rabbit antiserum was raised in Amsterdam against that isoenzyme of acid phosphatase (EC 188.8.131.52) which is usually designated prostatic acid phosphatase (PAP). The antigen used consisted of purified seminal plasma from vasectomized men. This antiserum has been extensively documented (1,2). The antiserum has been used principally in the field of histopathology and clinical chemistry.
KeywordsAcid Phosphatase Prostatic Carcinoma Seminal Plasma Adenoid Cystic Carcinoma Prostatic Acid Phosphatase
Unable to display preview. Download preview PDF.
- 3.M.A.M. Abdul-Fadl and E.J. King, Properties of the acid phosphatases of erythrocytes and of the human prostate gland, Biochem. J. 45: 51 (1949).Google Scholar
- 7.L.A. Sternberger, “Immunocytochemistry,” 2nd Edition, John Wiley and Sons, New York (1979).Google Scholar
- 11.B.K. Choe, E.J. Pontes, N.R. Rose, and M.D. Henderson, Expression of human prostatic acid phosphatase in a pancreatic islet cell carcinoma. Invest. Urol. 15: 312 (1977).Google Scholar
- 17.R.A. Watson and D.B. Tang, Diagnosis of prostatic cancer, New Engl. J. Med. 304: 51 (1980).Google Scholar