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Use of T Cell Hybridomas in the Analysis of Helper T Cell Functions in B Cell Responses

  • Neal Roehm
  • John Kappler
  • Philippa Marrack
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 150)

Abstract

The fundamental question under investigation is to determine the role of helper T cells in the induction of B cell antibody synthesis. Based on our previous work we have proposed that helper T cells mediate two types of helper functions; the production of antigen non-specific factors i.e. lymphokines and antigen specific help 1,2.

Keywords

Spleen Cell Keyhole Limpet Hemocyanin Soluble Antigen Helper Activity Primed Lymph Node 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Neal Roehm
    • 1
  • John Kappler
    • 1
  • Philippa Marrack
    • 1
  1. 1.Department of MedicineNational Jewish Hospital and Research CenterDenverUSA

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