Biosynthesis and Metabolism of Prostaglandins in Human Kidney in Vitro

  • Aviv Hassid
  • Michael Dunn


The importance of prostaglandins (PGs) in renal physiology is becoming increasingly appreciated.1 The vasoactivity of renal PGs and their interactions with the rennin-angiotensin system seem to be particularly well established. Specific renal effects of PGE2, PGI2, and thromboxane (TX) A2 have been proposed, whereas PGF appears to be largely biologically inert.


Cytosolic Fraction Human Kidney Microsomal Protein Rabbit Kidney Cortical Tubule 
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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Aviv Hassid
    • 1
  • Michael Dunn
    • 1
    • 2
  1. 1.Department of MedicineCase Western Reserve UniversityClevelandUSA
  2. 2.Division of NephrologyUniversity Hospitals of ClevelandClevelandUSA

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