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Inheritance of Oligomycin Resistance in Tissue Culture Cells

  • Jerome M. Eisenstadt
  • Mary C. Kuhns

Abstract

The mitochondrial ATPase complex has been resolved into the soluble F1, having the catalytic site for ATP synthesis, and the hydrophobic membrane-integrated F0, involved in proton translocation (Senior, 1973; Koslov and Skulacher, 1977). The F0 has been studied with the use of oligomycin and dicyclohexylcarbodiimide (DCCD), which inhibit enzyme activity of the complex by acting on a component of F0, (Bulos and Racker, 1968; Roberton et al., 1968; Sebald et al., 1976, 1979; Kiehl and Hatefi, 1980).

Keywords

Mitochondrial Genome Neurospora Crassa Aspergillus Nidulans Tissue Culture Cell Cloning Efficiency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Jerome M. Eisenstadt
    • 1
  • Mary C. Kuhns
    • 1
  1. 1.Department of Human GeneticsYale University School of MedicineNew HavenUSA

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