Future Perspectives in Somatic Cell Genetics

  • Doris L. Slate
  • Frank H. Ruddle


Somatic cell genetic techniques have proven valuable in determining the arrangement of genes on chromosomes and in studying the regulation of eukaryotic gene expression. Studies with somatic cells taken from patients with inherited diseases have revealed the biochemical bases for many human disorders, and have provided potential strategies for diagnostic and therapeutic approaches. The generation of mutants or variants of somatic cells in culture can facilitate the analysis of complex physiologic systems via complementation analysis.


Gene Transfer Cell Hybrid Recipient Cell Mouse Mammary Tumor Virus Mediate Gene Transfer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Doris L. Slate
    • 1
  • Frank H. Ruddle
    • 1
  1. 1.Department of BiologyYale UniversityNew HavenUSA

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