Detection of Specific DNA Sequences in Somatic Cell Hybrids and DNA Transfectants

  • Nancy Hsiung
  • Raju Kucherlapati


One of the methods to study gene expression in mammalian cells is to introduce the desired gene or genes into an appropriate recipient mammalian cell. There are several methods to introduce foreign genes into mammalian cells. These include somatic cell hybridization of whole cells, fusion of whole cells with microkaryoplasts, chromosome transfer, chromatin transfer, and DNA transfer.


Somatic Cell Hybrid Nick Translation Cesium Chloride Plastic Strip Geiger Counter 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Nancy Hsiung
    • 1
  • Raju Kucherlapati
    • 1
  1. 1.Department of Biochemical SciencesPrinceton UniversityPrincetonUSA

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