On the Selection of Animal Species as Models for Atherosclerosis Research, with Particular Reference to the Common Marmoset (Callithrix Jacchus)
Much has been written in recent years of the complex and multiple processes implicated in the development of atherosclerosis. Despite such intense activity in this field however, it is evident from the present Conference that controversy still sorrounds many aspects of this insidious disease. One may especially cite questions sorrounding the nature and relative importance of the various factors which may contribute to the initiation of the atherogenic process itself, as well as those relevant to its regression.
KeywordsSquirrel Monkey Familial Hypercholesterolemia Common Marmoset Experimental Atherosclerosis Patas Monkey
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- Anitschkow, N.N., 1967, A history of experimentation on arterial atherosclerosis in animals, in “Cowdry’s Atherosclerosis: a survey of the problem”, H.T. Blumenthal, ed.,C.C. Thomas, Springfield,Illinois,U.S.A.Google Scholar
- Chapman, M.J.,McTaggart, F.,and Goldstein, S., 1979, Density distribution, characterisation and comparative aspects of the major serum lipoproteins in the Common Marmoset ( Callithrix jacchus), a New World primate with potential use in lipoprotein research, Biochemistry, 18: 5096PubMedCrossRefGoogle Scholar
- Chapman, K.P.,Stafford, W.W.,and Day, C.E., 1976, Animal models for experimental atherosclerosis produced by selective breeding of Japanese Quail, in “Atherosclerosis Drug Discovery”, C.E. Day,ed., Plenum Press,New YorkGoogle Scholar
- Fredrickson, D.S.,Goldstein, J.L.,and Brown, M.S., 1978, The familial hyperlipoproteinemias, in “The Metabolic Basis if Inherited Disease”, J.B. Steinbury, J.B. Wyngaarden and D.S. Fredrickson,,4th edition,McGraw-Hill, New YorkGoogle Scholar
- Illingworth, D.R., 1975, Metabolism of lipoproteins in nonhuman primates. Studies on the origin of low density lipoprotein apoprotein in the plasma of the squirrel monkey, Biochim. Biophys.Acta, 338: 38Google Scholar
- Mahley, R.W., 1978, Alterations in plasma lipoproteins induced by cholesterol feeding in animals including man, in “Disturbances in Lipid and Lipoprotein Metabolism” J.M. Dietschy,A.M. Gotto and J.A. Ontko,eds.,Am.Physiol.Soc., BethesdaGoogle Scholar
- Mills, G.L.,Taylaur, C.E.,and Chapman, M.J., 1976, Low-density lipo-proteins in patients homozygous for familial hyperbetalipo- proteinemia, Clin.Sci.Mol.Med., 51: 221Google Scholar
- Mills, G.L.,and McTaggart, F., 1974, Characterization of experimental Type II hyperlipoproteinemia in guinea pigs, in “Atherosclerosis III”, G. Schettler and A. Weizel,eds.,Springer-Verlag, BerlinGoogle Scholar
- Roberts, A.,and Thompson, J.S., 1976, Inbred mice and their hybrids as an animal model for atherosclerosis research, in “Atherosclerosis Drug Discovery”,C.E. Day,ed., Plenum Press,New YorkGoogle Scholar
- Scanu, A.M.,Edelstein, C.,Vitello, L.,Jones, R.,and Wissler, R.W., 1973, The serum high density lipoproteins of Macacus rhesus I. Isolation, composition and properties, J.Biol.Chem., 218: 7648Google Scholar
- Shore, B.,and Shore, V., 1976, Rabbits as a model for the study of hyper-lipoproteinemia and Atherosclerosis, in “Atherosclerosis Drug Discovery”, C.E. Day,ed., Plenum Press, New York.Google Scholar
- Srinivasan, S.R., Smith, C.C.,Rashakrishnamurthy, B.,Wolf, R.H.,and Berenson, G.S., 1976, Phylogenetic variability of serum lipids and lipoproteins in nonhuman primates fed diets with different contents of dietary cholesterol, Adv.Exp.Biol.Med., 67: 65Google Scholar