Abnormal Tubular Pi Adaptation to Dietary Pi Restriction and Decreased Calcium Reabsorption in X-Linked Hypophosphatemic (HYP) MICE
The renal transport of Pi is under a powerful parathyroid hormone-independent adaptation mechanism (1,2). It has been suggested (3) that this adaptation mechanism could be defective in X-linked hypophosphatemia, a disease characterized by vitamin D-resistant rickets and decreased tubular reabsorption of Pi (4).
KeywordsRenal Handling Phosphate Reabsorption Phosphate Diet High Phosphate Diet Reabsorptive Capacity
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