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Effect of Parathyroid Hormone on Rat Enterocyte Na Transport in Vitro

  • T. Drüeke
  • B. Lacour
  • E. Pierandrei
  • J. Chanard
  • J. L. Funck-Brentano
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 151)

Abstract

Parathyroid Hormone (PTH) influences renal (1,2) and intestinal (3,4) handling of Na and water. In the intestine, it is not clearly established whether the observed effects are due to a direct action of the hormone or whether they are indirect via other mediators.

Keywords

Parathyroid Hormone Incubation Medium Trichloroacetic Acid Solution Renal Cortical Slice Efflux Rate Constant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Amiel, C., Kuntziger, H. and Richet, G., Phosphate by proximal and distal nephron in normal and parathyroidectomized rats. Evidence for distal reabsorption, Pflugers Arch. 317:93 (1970).PubMedCrossRefGoogle Scholar
  2. 2.
    Dennis, V.W., Influence of bicarbonate on parathyroid hormone-induced changes in fluid absorption by the proximal tubule, Kidney Int. 10:373 (1976).PubMedCrossRefGoogle Scholar
  3. 3.
    Drueke, T., LaCour, B., and Chanard, J., Acute inhibitory effect of parathyroid hormone and calcitonin on jejunal electrolyte and water transport in normal and thyroparathyroidectomized rats, Miner. Elect. Metab. 4:68 (1980).Google Scholar
  4. 4.
    Lacour, B., Drueke, T. and Chanard, J., Effect of parathyroid hormone on jejunal electrolyte and water transport and cyclic nucleotide formation in the rat, Horm. Metab. Res. 12:624 (1980).PubMedCrossRefGoogle Scholar
  5. 5.
    Levine, P.H. and Weintraub, L.R., Preparation of suspensions of small bone mucosal epithelial cells, J. Lab. Clin. Med. 75: 1026 (1970).PubMedGoogle Scholar
  6. 6.
    Gall, D.G., Butler, D.G., Teppermann, F.S. and Hamilton, J.R., Sodium ion transport in isolated intestinal epithelial cells. The effect of actively transported sugars on sodium ion efflex. Biochim. Biophys. Acta. 339:291 (1974).PubMedCrossRefGoogle Scholar
  7. 7.
    Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J., Protein measurement with the Folin phenol reagent, J. Biol. Chem. 193:265 (1951).PubMedGoogle Scholar
  8. 8.
    Rosenberg, E.M., Lee, S.W., Chase, L.R. and Avioli, L.V., Phosphate accumulation by the isolated renal tubule and the effects of parathyroid hormone and cyclic adenosine monophosphate, J. Lab. Clin. Med. 96:24 (1980).PubMedGoogle Scholar
  9. 9.
    Krieger, N.S. and Tashjian, A.H. Jr., Parathyroid hormone stimulates bone resorption via a Na-Ca exchange mechanism, Nature 287:843 (1980).PubMedCrossRefGoogle Scholar
  10. 10.
    Rosenberg, E.M. and Fogel, A.J., Role of cyclic 3′,5′-GMP in modulation of cellular uptake of phosphate, Am. J. Physiol. 233:E203 (1977).PubMedGoogle Scholar
  11. 11.
    Rasmussen, H. and Goodman, D.B.P., Relationship between calcium and cyclic nucleotides in cell activation, Physiol. Rev. 57:421 (1977).PubMedGoogle Scholar
  12. 12.
    Borle, A. and Uchikawa, T., Effects of parathyroid hormone on the distribution and transport of calcium in cultured kidney cells, Endocrinology 102:1725 (1978).PubMedCrossRefGoogle Scholar
  13. 13.
    Taylor, A. and Windhager, E.E., Possible role of cytosolic calcium and Na-Ca exchange in regulation of transepithelial sodium transport, Am. J. Physiol. 236:F505 (1979).PubMedGoogle Scholar
  14. 14.
    Lee, C.O., Taylor, A. and Windhager, E.E., Cytosolic calcium ion activity in epithelial cells of Necturus kidney, Nature 287:859 (1980).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • T. Drüeke
    • 1
    • 2
  • B. Lacour
    • 1
    • 2
  • E. Pierandrei
    • 1
    • 2
  • J. Chanard
    • 1
    • 2
  • J. L. Funck-Brentano
    • 1
    • 2
  1. 1.INSERM U 90Hôpital NeckerParisFrance
  2. 2.CHU ReimsFrance

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