Effects of 1,25-Dihydroxy Vitamin D3 in Patients with Early Renal Failure
Patients with chronic renal failure commonly develop secondary hyperparathyroidism as creatinine clearances decrease to less than 30 ml/min.1 However, biochemical abnormalities have also been noted in patients with early renal failure (ERF), with higher creatinine clearances (30 to 90 ml/min). These abnormalities include hypocalcemia, hypophosphatemia, and elevated serum levels of parathyroid hormone (PTH).2-4 Such abnormalities indicate that secondary hyperparathyroidism may be present even in the early stages of chronic renal failure.
KeywordsChronic Renal Failure Secondary Hyperparathyroidism Serum Phosphate Urinary Phosphate Excretion Sodium Potassium Phosphate
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