Metabolic Abnormalities Underlying the Pathogenesis of Vitamin D Resistant Rickets (VDRR)

  • Michele G. Brunette
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 151)


Until recently, human investigation was the only means to study the pathogenesis of VDRR. In 1976 the discovery of a mouse model by Eicher et al facilitated the study of this disease. After five years, a substantial amount of data has accumulated, which will be summarized here.


Brush Border Membrane Proximal Convoluted Tubule Hypophosphatemic Rickets Transport Defect Phosphate Depletion 


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Michele G. Brunette
    • 1
  1. 1.Maisonneuve-Rosemont Hospital, Dept. of Pediatrics Faculty of MedicineUniv. of MontrealMontrealCanada

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