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Targeting of Drugs pp 337–353Cite as

Therapeutic Potential of Liposomes as Carriers in Leishmaniasis, Malaria, and Vaccines

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Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 47))

Abstract

Since the first suggestion, approximately ten years ago, that lipid vesicles might have practical uses in medicine, liposomes have been a treatment in search of a disease. The approach of my laboratory since 1976 has been to search for clinical applications among infectious diseases. Because parenterally injected liposomes natually travel in great amounts to the liver and spleen I felt, at least at the beginning of our research, that attempts to tailor liposomes to particular diseases by artificially targeting the vesicles to areas other than the liver and spleen, might be difficult. Therefore, my colleagues and I have concentrated only on diseases in which the liver and spleen play an important, or even a crucial, role.

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Authors and Affiliations

  1. Department of Membrane Biochemistry, Walter Reed Army Institute of Research, Washington, DC, 20012, USA

    Carl R. Alving

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  1. Carl R. Alving
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Editors and Affiliations

  1. Clinical Research Centre, Harrow, UK

    Gregory Gregoriadis  & Judith Senior  & 

  2. International Institute of Cellular and Molecular Pathology, Brussels, Belgium

    André Trouet

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© 1982 Plenum Press, New York

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Alving, C.R. (1982). Therapeutic Potential of Liposomes as Carriers in Leishmaniasis, Malaria, and Vaccines. In: Gregoriadis, G., Senior, J., Trouet, A. (eds) Targeting of Drugs. NATO Advanced Study Institutes Series, vol 47. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4241-0_20

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  • DOI: https://doi.org/10.1007/978-1-4684-4241-0_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4243-4

  • Online ISBN: 978-1-4684-4241-0

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