Abstract
Liposomes are artificially prepared spheres of concentric phospholipid bilayers separated by aqueous compartments. They form when water insoluble phospholipids are confronted with water. The phospholipid molecules try to reach a conformation in which their hydrophobic fatty acid groups are not in direct contact with water. The formation of phospholipid bilayers in which the relatively hydrophylic head groups are localized on both outer parts of the bilayers, whereas the hydrophobic fatty acid groups are localized directly opposite to each other in the inner part of the bilayer is a logical consequence.
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van Rooijen, N., van Nieuwmegen, R. (1982). Immunoadjuvant Properties of Liposomes. In: Gregoriadis, G., Senior, J., Trouet, A. (eds) Targeting of Drugs. NATO Advanced Study Institutes Series, vol 47. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4241-0_18
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