Dynamics of Peptides and Proteins

  • Martin Karplus
Part of the NATO Advanced Study Institutes Series book series (NSSA, volume 45)


An essential question in any attempt to understand the biological function of peptides and proteins concerns the dynamics of their structural fluctuations and conformational changes. The motions that occur range from small local atom displacements, sidechain reorientations and main chain fluctuations, through almost rigid body movements of domains and subunits to the folding and unfolding transition involving the entire polypeptide chain. It is important to know how these motions take place and what the time scales of the motions are.


Dihedral Angle Temperature Factor Langevin Equation Ring Rotation Globular Domain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Martin Karplus
    • 1
  1. 1.Department of ChemistryHarvard UniversityCambridgeUSA

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