Survey of Calcium Action in Stimulus-Secretion Coupling
Before we survey the plethora of information concerning the regulatory role of calcium in the secretory process, it is necessary to review briefly the general features of this process in order to better appreciate how calcium acts in secretory systems. Under electron-microscopic analysis a typical feature of the secretory cell is the presence of numerous membrane-bound granules (100–400 nm in diameter) scattered throughout the cytoplasm that contain a variable quantity of electron-dense material. Small granular vesicles are also a uniform feature at chemical synapses, being situated close to the presynaptic nerve terminal.
KeywordsAcinar Cell Adrenal Medulla Extracellular Calcium Secretory Response Enzyme Release
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