Drug- and Toxin-Induced Nephritides

Anti-Kidney Antibody and Immune Complex Mediation
  • Curtis B. Wilson


Current evidence suggests that drugs and toxins can damage the kidney through humoral immunologic mechanisms. These pathways of nephritogenic humoral immune injury will be described in this chapter, and several ways in which drugs and toxins potentially play a role will be outlined. Particular attention will be given to hydrocarbons as a toxic agent that has been reported to induce at least one kind of anti-kidney antibody response, namely that directed toward the renal basement membranes.


Immune Complex Glomerular Basement Membrane Tubulointerstitial Nephritis Immune Complex Deposit Glomerular Capillary Wall 
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Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • Curtis B. Wilson
    • 1
  1. 1.Department of ImmunopathologyResearch Institute of Scripps ClinicLa JollaUSA

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