Antihistone Antibodies Induced by Procainamide and Hydralazine
It is well documented that symptoms resembling those of systemic lupus erythematosus (SLE) as well as antinuclear antibodies (ANAs) may appear in patients undergoing prolonged drug therapy (Weinstein, 1980; Blomgren, 1973; Tan, 1974). Several drugs differing in molecular structure and metabolic pathways of biotransformation have been implicated (Lee and Chase, 1975).
KeywordsSystemic Lupus Erythematosus Antinuclear Antibody Nonhistone Protein Polystyrene Tube Antihistone Antibody
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