Over three decades have elapsed since the identification of Chlortetracycline, the first tetracycline antibiotic. Since that time a large number of other tetracycline congeners have been isolated (from the products of fungal fermentation) and synthesized (by chemical alterations of the basic molecule). Seven congeners are currently available as broad-spectrum antibiotics in the United States: Chlortetracycline (CTC), Oxytetracycline (OTC), tetracycline (TC), demeclocycline (DMCTC), methacycline (MOTC), doxycycline (DOOTC), and minocycline (DDDTC)


Adenylate Cyclase Nephrogenic Diabetes Insipidus Fanconi Syndrome Renal Epithelium Toad Urinary Bladder 


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Copyright information

© Springer Science+Business Media New York 1982

Authors and Affiliations

  • Malcolm Cox
    • 1
  1. 1.Renal-Electrolyte Section, Department of MedicinePhiladelphia Veterans Administration Medical Center and University of Pennsylvania School of MedicinePhiladelphiaUSA

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