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Receptor Mapping by Histochemistry

  • James K. Wamsley
  • Jose M. Palacios

Abstract

The ability to apply receptor binding techniques to the localization of neurotransmitter receptors at the microscopic level has opened new avenues of research into the sites of drug and neurotransmitter action. Originally, localizations of this nature required the availability of irreversibly or nearly irreversibly binding ligands specific for the receptor of interest. The development of new techniques allowing the discrete localization of binding sites for diffusible substances has been a major advance in this field and will undoubtedly prove to be a useful adjunct to future studies involving the analysis of neurotransmitter pathways in the nervous system.

Keywords

Dentate Gyrus Hippocampal Formation Opiate Receptor Muscarinic Cholinergic Receptor Stratum Oriens 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • James K. Wamsley
    • 1
  • Jose M. Palacios
    • 2
  1. 1.Departments of Psychiatry and AnatomyUniversity of UtahSalt Lake CityUSA
  2. 2.Department of NeuroscienceThe Johns Hopkins University, School of MedicineBaltimoreUSA

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