Long-Term Survivors after Renal Transplantation

  • Carl M. Kjellstrand
  • Richard L. Simmons


During the past two decades renal transplantation has become an established clinical procedure performed in a large number of hospitals. Over 20,000 transplants were reported to the European Dialysis and Transplant Association as of January 1, 1979,1 and at least 35,000 transplants were performed in the United States through 1979. The early problems, mainly related to insufficient dialysis preparation, overimmuno-suppression, and infections, have been described in hundreds of articles over the past decade. This clinical research has led to a marked improvement in the immediate post-transplant survival. Thus many centers report an improvement from approximately a 10%–20% first-year survival during the early 1960s to a first-year patient survival of around 90% in the late 1970s.2


Renal Transplantation Transplant Proc Chronic Rejection Chronic Dialysis Maintenance Hemodialysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Brunner FP, Brynger H, Chantler C, et al: Combined report on regular dialysis and transplantation in Europe, IX, 1978. Proc Eur Dialysis Transplant Assoc 16: 2 - 73, 1979.Google Scholar
  2. 2.
    Kjellstrand CM, Avram MM, Blagg CR, et al: Cadaver transplantation versus hemodialysis. Trans Am Soc Artif Intern Organs 26: 611 - 624, 1980.PubMedGoogle Scholar
  3. 3.
    Matas AJ, Simmons RL, Buselmeier TJ, et al: The fate of patients surviving three years after renal transplantation. Surgery 80: 390 - 395, 1976.Google Scholar
  4. 4.
    Weil R, Schroter CPJ, West JC, et al: A 14-year experience with kidney transplantation. World J Surg 1: 145 - 149, 1977.CrossRefGoogle Scholar
  5. 5.
    Blohme I, Ahlmen J, Sandberg L: Prognosis for recipients of successful renal transplants. Scand J Urol Nephrol 38 (suppl): 89 - 98, 1976.Google Scholar
  6. 6.
    Thomas FT, Lee HM: Factors in the differential rate of arteriosclerosis between long surviving renal transplant recipients and dialysis patients. Ann Surg 184: 342 - 351, 1976.PubMedCrossRefGoogle Scholar
  7. 7.
    Opelz G, Mickey MR, Terasaki PI: Calculations of longterm graft and patient survival in human kidney transplantation. Transplant Proc 9: 27 - 30, 1977.PubMedGoogle Scholar
  8. 8.
    Wing AL Brunner FP, Brynger H, et al: Combined report on regular dialysis and transplantation in Europe, 1977. Proc Eur Dialysis Transplant Assoc 15: 4 - 76, 1978.Google Scholar
  9. 9.
    Burke JF, Francos GC, Morre LL, et al: Accelerated atherosclerosis in chronic dialysis patients-Another look Nephron 21: 181 - 185, 1978.Google Scholar
  10. 10.
    Lundin AP, Adler AJ, Feinroth MV, et al: Maintenance hemodialysis. JAMA 244: 38 - 40, 1980.PubMedCrossRefGoogle Scholar
  11. 11.
    Vincenti F, Amend WJ, Abele J, et al: The role of hypertension in hemodialysis associated atherosclerosis. Am J Med 68: 363 - 369, 1980.PubMedCrossRefGoogle Scholar
  12. 12.
    Rostad SG, Gretes JC, Kirk KA, et al: Ischemic heart disease in patients with uremia undergoing maintenance hemodialysis. Kidney Int 16: 600 - 611, 1979.CrossRefGoogle Scholar
  13. 13.
    Ibels LS, Stewart JH, Mahony JF, et al: Deaths from occlusive arterial disease in renal allograft recipients. Br Med J 3: 552 - 554, 1974.PubMedCrossRefGoogle Scholar
  14. 14.
    Kjellstrand CM: Side effects of steroids and their treatment. Transplant Proc 7: 123 - 129, 1975.Google Scholar
  15. 15.
    McGeown MG, Douglas JF, Brown WA, et al: Advantages of low dose steroid from the day after renal transplantation. Transplant 29: 287 - 289, 1980.CrossRefGoogle Scholar
  16. 16.
    Chan L, French ME, Beare J, et al: Prospective trial of high dose versus low dose prednisolone in renal transplant patients. Transplant Proc 12: 323 - 326, 1980.PubMedGoogle Scholar
  17. 17.
    Salvatierra O, Potter D, Cochrum KC, et al: Improved patient survival in renal transplantation. Surgery 79: 166 - 171, 1976.PubMedGoogle Scholar
  18. 18.
    Zoller KM, Cho SI, Cohen JJ, et al: Cessation of immunosuppressive therapy after successful transplantation: A national survey. Kidney Int 18: 110 - 114, 1980.PubMedCrossRefGoogle Scholar
  19. 19.
    Nielsen V, Clausen E, Ranek L: Liver impairment during chronic hemodialysis and after renal transplantation. Acta Med Scand 197: 229 - 234, 1975.PubMedCrossRefGoogle Scholar
  20. 20.
    Anuras S, Piros J, Bonney WW, et al: Liver disease in renal transplant recipients. Arch Intern Med 137: 42 - 48, 1977.PubMedCrossRefGoogle Scholar
  21. 21.
    Ware AJ: Etiology of liver disease in renal transplant patients. Ann Intern Med 91: 364 - 371, 1979.PubMedGoogle Scholar
  22. 22.
    Mozes MF, Ascher NL, Balfour HH, et al: Jaundice after renal allotransplantation. Ann Surg 188: 783 - 790, 1978.PubMedCrossRefGoogle Scholar
  23. 23.
    Shideman J, Najarian JS, Simmons RL, et al: Longterm survival and complications more than 10 years following renal transplantation, in Giordano C, Friedman EA (eds) Uremia: Pathobiology of Patients Treated for 10 Years or More, Milan, Italy, Wichtig Editore, 1981, pp. 142 - 151.Google Scholar
  24. 24.
    Lindner A, Charra B, Sherrard DJ, et al: Accelerated atherosclerosis in prolonged maintenance hemodialysis. N Engl J Med 290: 697 - 701, 1974.PubMedCrossRefGoogle Scholar
  25. 25.
    Posborg Petersen V, Steen Olsen T, Kissmeyer-Nielsen F, et al: Late failure of human renal transplants. Medicine 54: 45 - 71, 1975.CrossRefGoogle Scholar
  26. 26.
    Halgrimson CG, Penn I, Booth A, et al: Eight-to-ten year follow-up in early cases of renal homotransplantation. Transplant Proc 5: 787 - 791, 1973.PubMedGoogle Scholar
  27. 27.
    Thomas F, Lee HM, Wolf JS, et al: Long-term (8-12 years) prognosis in related and unrelated renal transplantation. Transplant Proc 7: 707 - 711, 1975.Google Scholar

Copyright information

© Plenum Publishing Corporation 1982

Authors and Affiliations

  • Carl M. Kjellstrand
    • 1
    • 2
  • Richard L. Simmons
    • 3
  1. 1.Division of Nephrology, Departments of Medicine and SurgeryUniversity of MinnesotaMinneapolisUSA
  2. 2.Nephrology Division, Regional Kidney Disease ProgramHennepin County Medical CenterMinneapolisUSA
  3. 3.Department of SurgeryUniversity of Minnesota HospitalsMinneapolisUSA

Personalised recommendations