Prognosis and Prevention of Renal Failure Induced by Toxins
Deleterious functional effects caused by nephrotoxins can result when such noxious agents induce renal failure de novo, either acutely or chronically, or when preexisting impairment of renal function is aggravated by toxin exposure. Severe acute renal failure can usually be recognized easily. Moreover, the association with acute toxin exposure is often apparent, although its role may not be appreciated in patients with coexistent problems such as septicemia and shock. Chronic nephrotoxicity and toxicity superimposed on chronic renal impairment are frequently more difficult to diagnose.
KeywordsAcute Renal Failure Interstitial Nephritis Nephrogenic Diabetes Insipidus Fanconi Syndrome Acute Interstitial Nephritis
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- 1.Maher JF: Toxic and irradiation nephropathies, in Earley LE, Gottschalk CW (eds): Strauss and Welt’s Diseases of the Kidney. Boston, Little, Brown and Co, 1978, pp 1431–1474.Google Scholar
- 11.Farebrother DA, Hatfield P, Simmonds HA, et al: Experimental crystal nephropathy (one year study in the pig). Clin Nephrol 4: 243–250, 1975.Google Scholar
- 20.Wainscoat JS, Finn R: Possible role of laxatives in analgesic nephropathy. Br Med J 4: 697698, 1974.Google Scholar
- 30.Nanra RS, Fairley KF, Kincaid-Smith P: Recovery of function in patients with analgesic nephropathy. Aust Ann Med 19: 195–196, 1970.Google Scholar
- 32.Ho PWL, Pien FD, Kominami N: Massive amikacin “overdosage.” Ann Intern Med 91: 227228, 1979.Google Scholar