Introduction Historical and General Comments
Hundreds of years ago, the Greek physician Parmenides said that given the means to induce fevers he would be able to cure all illnesses. Presumably he meant to include cancer, since malignancies were described in early Greek literature. The effects of elevated temperatures on human physiological functions and, in particular, on the healing process have fascinated clinicians and researchers for many years. Hippocrates described in detail many febrile diseases and commented extensively on the beneficial role of fever. A Roman, Celsus, catalogued the clinical symptoms of inflammation and noticed their association with fevers.
KeywordsMalignant Hyperthermia Sodium Salicylate Deuterium Oxide Febrile Disease Central Nervous System Symptom
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