Analysis of Functional Cell Sets in the Immune System
In the immune system it has been possible to distinguish subpopulations of cells on the basis of the surface antigens they express. The genetic program of each set of cells combines information which codes for a unique pattern of cell surface glycoproteins that is invariably associated with a particular immunologic function. More recently, it has been possible to identify the functional role of one of these surface glycoproteins. The purpose of this article is to review the experimental approaches which have contributed to the definition of functional cell sets in the immune system in the hope that similar strategies may be useful in the dissection of functionally relevant cell sets in the nervous system.
KeywordsGenetic Program Cell Surface Glycoprotein Kill Target Cell Lymphocyte Clone Syngeneic Cell
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