Alcohol, Amino Acids, and Encephalopathy

  • Spencer Shaw
  • Charles S. Lieber


Encephalopathy is a severe and common complication of cirrhosis, including alcoholic cirrhosis, but its pathogenesis is not fully understood. Several new theories have been proposed, and many have emphasized the importance of plasma amino acids. Recent studies have called into question the hypothesis that the ratio of aromatic to branched-chain amino acids in plasma is the key abonormality in this disorder.


Hepatic Encephalopathy Plasma Amino Acid Hepatic Coma Idiopathic Portal Hypertension Chronic Alcohol Consumption 


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Copyright information

© Plenum Publishing Corporation 1982

Authors and Affiliations

  • Spencer Shaw
    • 1
    • 2
  • Charles S. Lieber
    • 1
    • 2
  1. 1.Mount Sinai School of Medicine of the CityUniversity of New YorkNew YorkUSA
  2. 2.Alcohol Research and Treatment Center, Bronx Veterans Administration Medical CenterNew YorkUSA

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