Ontogeny of Amphibian Hemopoietic Cells

  • James B. Turpen
  • Nicholas Cohen
  • Pierre Deparis
  • André Jaylet
  • Robert Tompkins
  • E. Peter Volpe


The developmental origin of lymphoid cells of vertebrates continues to be a fascinating, perplexing problem. Historically, the disputable issues have revolved around two fundamental aspects: the origin of the precursors of the various types of differentiated blood cells and the lineal relationships among these different cell types. There are special features of amphibians that make them suitable for clarifying the embryogenesis of hemopoietic cells. An array of microsurgical techniques from experimental embryology can be used to marked advantage. In this chapter, we will review the contributions made by investigators who have used the tools of experimental embryology to gain insight into the ontogeny of vertebrate blood cells.


Hemopoietic Stem Cell Hemopoietic Cell Leopard Frog Thymus Gland Blood Island 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • James B. Turpen
    • 1
  • Nicholas Cohen
    • 2
  • Pierre Deparis
    • 3
  • André Jaylet
    • 3
  • Robert Tompkins
    • 4
  • E. Peter Volpe
    • 5
  1. 1.Department of BiologyPennsylvania State UniversityUniversity ParkUSA
  2. 2.Department of Microbiology, Division of ImmunologyUniversity of Rochester School of Medicine and DentistryRochesterUSA
  3. 3.Laboratoire de Biologie généraleUniversité Paul SabatierToulouse CedexFrance
  4. 4.Department of BiologyTulane UniversityNew OrleansUSA
  5. 5.Department of Basic Medical Sciences, School of MedicineMercer UniversityMaconUSA

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